Lectures (Video)
- 1. Diseases and Disease Databases
- 2. Genomics
- 3. Genome Database
- 4. Single Nucleotide Polymorphisms (SNP)
- 5. Structural Genomic Variations
- 6. Gene Expression
- 7. miRNA Regulatory Network
- 8. Bioinformatics
- 9. Stem Cell
- 10. Gene Therapy
- 11. Value Chain for Drug Development
- 12. Can big pharma change to benefit patients?
- 13. Protein Architecture
- 14. Protein Fold
Genomics and Medicine
Course Summary
This course is based on Biochemistry 118 made available by Douglas L. Brutlag (Stanford University) under the Creative Commons Attribution 2.0 license.
This course discusses the kind of knowledge we hope to gain from sequencing human and bacterial genomes and the implications of such knowledge for medicine and biomedical research. We will discuss novel diagnoses and treatment of diseases, including stem cells, gene therapy and rational drug design. We will also discuss the ethical implications of genetic information.
The course will be of interest to students who plan to major in biology or human biology, especially premedical students and biology majors who use molecular biology methods. It will also be useful to those interested in health care policy, intellectual-property rights and ethical issues.
This course is taught by Douglas L. Brutlag who is Professor of Biochemistry & Medicine in Stanford University School of Medicine.
Reading Material
1. A Primer of Genome Science, Third EditionGreg Gibson and Spencer V. Muse, A Primer of Genome Science, Third Edition, 2009, Sinauer Associates, ISBN: 9780878932368
Course Material
Not available.Other Resources
1. Genomics and World Health: Report of the Advisory Committee on Health ResearchWorld Health Organization - Advisory Committee on Health Research, Genomics and World Health: Report of the Advisory Committee on Health Research, WHO, 2002, ISBN 9789241545549
(Click the button below to see a preview of the book)
2. Genomics: The science and technology behind the Human Genome Project
Charles R. Cantor, Cassandra L. Smith, Genomics: The science and technology behind the Human Genome Project, John Wiley and Sons, 1999, ISBN: 9780471599081
(Click the button below to see a preview of the book)
3. Bioinformatics: Sequence and Genome Analysis
David W. Mount, Bioinformatics: Sequence and genome analysis, CSHL Press, 2004, ISBN 9780879697129
(Click the button below to see a preview of the book)
4. Bioinformatics Computing
Bryan P. Bergeron, Bioinformatics Computing, Prentice Hall PTR, 2002, ISBN 9780131008250
(Click the button below to see a preview of the book)
