Lectures
- 1. Physical Structure of the Gene
- 2. Complementation Test and Gene Function
- 3. Mendelian Genetics
- 4. Probability and Pedigrees
- 5. Chromosomes and Sex Linkage
- 6. Recombination and Genetic Maps
- 7. Three-factor Crosses
- 8. Tetrad Analysis
- 9. Phage Genetics
- 10. Gene Structure and DNA Analysis
- 11. Mutations and Suppressors
- 12. Bacterial Genetics: Transposition
- 13. Bacterial Genetics: Transduction
- 14. Complementation in Bacteria: Plasmids
- 15. Complementation in Bacteria: Recombinant DNA
- 16. Prokaryotic Regulation: Negative Control
- 17. Prokaryotic Regulation: Positive Control
- 18. Prokaryotic Regulation: Regulatory Circuits
- 19. Eukaryotic Genes and Genomes I
- 20. Eukaryotic Genes and Genomes II
- 21. Eukaryotic Genes and Genomes III
- 22. Eukaryotic Genes and Genomes IV
- 23. Transgenes and Gene Targeting in Mice I
- 24. Transgenes and Gene Targeting in Mice II
- 25. Population Genetics: Hardy-Weinberg
- 26. Population Genetics: Mutation and Selection
- 27. Population Genetics: Inbreeding
- 28. Human Polymorphisms
- 29. Statistical Evaluation of Linkage I
- 30. Statistical Evaluation of Linkage II
- 31. Complex Traits
- 32. Chromosome Anomalies I
- 33. Chromosome Anomalies II
- 34. Genetics of Cancer I
- 35. Genetics of Cancer II
Genetics
Course Summary
This course is based on 7.03 Genetics, Fall 2004 made available by Massachusetts Institute of Technology: MIT OpenCourseWare under the Creative Commons BY-NC-SA license.
This course discusses the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. The topics include: structure and function of genes, chromosomes and genomes, biological variation resulting from recombination, mutation, and selection, population genetics, use of genetic methods to analyze protein function, gene regulation and inherited disease.
Reading Material
1. An Introduction to Genetic AnalysisGriffiths, Anthony J. F., Jeffrey H. Miller, David T. Suzuki, Richard C. Lewontin, and William M. Gelbart. An Introduction to Genetic Analysis. 7th ed. New York: W. H. Freeman, 2000. ISBN: 9780716735205.
An online version of this textbook is available here for searching.
Course Material
Not available.Other Resources
1. Genetics: Analysis of Genes and GenomesDaniel L. Hartl, Elizabeth W. Jones, Genetics: Analysis of Genes and Genomes, Edition 7, Publisher: Jones & Bartlett Publishers, 2008, ISBN: 9780763758684
(Click the button below to see a preview of the book)
Software
Not available.Discussion Forum
For discussion on this topic, please go to the relevant forum for Genetics. Click the button below to open the forum page in a new window.
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